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1

The Fluorinase from Streptomyces cattleya Is Also a Chlorinase

Hai Deng, Steven L. Cobb, Andrew R. McEwan, Ryan P. McGlinchey, James H. Naismith, David O'Hagan, David A. Robinson, Jonathan B. Spencer

Journal:

Angewandte Chemie

Year:

2006

Language:

english

File:

PDF, 189 KB

english, 2006

2

Weaving Objects: Spatial Design and Functionality of 3D-Woven Textiles

Harvey, Claire, Holtzman, Emily, Ko, Joy, Hagan, Brooks, Wu, Rundong, Marschner, Steve, Kessler, David

Journal:

Year:

2019

Language:

english

File:

PDF, 2.01 MB

english, 2019

3

Fluorinase mediated chemoenzymatic synthesis of [18F]-fluoroacetate

Li, Xiang-Guo, Domarkas, Juozas, O'Hagan, David

Journal:

Chemical Communications

Year:

2010

Language:

english

File:

PDF, 728 KB

english, 2010

4

US Expansionism: The Imperialist Urge in the 1890s

Hagan, Kenneth J., Healy, David

Journal:

The Journal of American History

Year:

1971

Language:

english

File:

PDF, 130 KB

english, 1971

5

Fluorinase-Coupled Base Swaps: Synthesis of [18F]-5′-Deoxy-5′-fluorouridines

Margit Winkler, Juozas Domarkas, Lutz F. Schweiger, David O'Hagan

Journal:

Angewandte Chemie

Year:

2008

Language:

english

File:

PDF, 336 KB

english, 2008

6

Synthesis and Structure of Stereoisomeric Multivicinal Hexafluoroalkanes

Luke Hunter, Peer Kirsch, Alexandra M. Z. Slawin, David O'Hagan

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 342 KB

english, 2009

7

Alicyclic Ring Structure: Conformational Influence of the CF2 Group in Cyclododecanes

Maciej Skibinski, Dr. Yi Wang, Prof. Alexandra M. Z. Slawin, Dr. Tomas Lebl, Prof. Dr. Peer Kirsch, Prof. David O'Hagan

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 633 KB

english, 2011

8

A regio- and stereoisomeric study of allylic alcohol fluorination with a range of reagents

Stefano Bresciani, Alexandra M.Z. Slawin, David O’Hagan

Journal:

Journal of Fluorine Chemistry

Year:

2009

Language:

english

File:

PDF, 311 KB

english, 2009

9

Engineering Fluorometabolite Production: Fluorinase Expression in Salinispora tropica Yields Fluorosalinosporamide †

Eustáquio, Alessandra S., O’Hagan, David, Moore, Bradley S.

Journal:

Journal of Natural Products

Year:

2010

Language:

english

File:

PDF, 1.23 MB

english, 2010

10

Tumour imaging by Positron Emission Tomography using fluorinase generated 5-[18F]fluoro-5-deoxyribose as a novel tracer

Dall'Angelo, Sergio, Bandaranayaka, Nouchali, Windhorst, Albert D., Vugts, Danielle J., van der Born, Dion, Onega, Mayca, Schweiger, Lutz F., Zanda, Matteo, O'Hagan, David

Journal:

Nuclear Medicine and Biology

Year:

2013

Language:

english

File:

PDF, 818 KB

english, 2013

11

Diastereoselective Synthesis of 2,3,4,5,6-Pentafluoroheptanes

Farran, Daniel, Slawin, Alexandra M. Z., Kirsch, Peer, O’Hagan, David

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 1.12 MB

english, 2009

12

Synthesis and structure of all-syn-1,2,3,4-tetrafluorocyclohexane

Durie, Alastair J., Slawin, Alexandra M. Z., Lebl, Tomas, Kirsch, Peer, O'Hagan, David

Journal:

Chemical Communications

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

13

Robust meta-analytic-predictive priors in clinical trials with historical control information

Schmidli, Heinz, Gsteiger, Sandro, Roychoudhury, Satrajit, O'Hagan, Anthony, Spiegelhalter, David, Neuenschwander, Beat

Journal:

Year:

2014

Language:

english

File:

PDF, 403 KB

english, 2014

14

Helping ELLs Meet the Common Core State Standards for Literacy in Science: The Impact of an Instructional Intervention Focused on Academic Language

August, Diane, Branum-Martin, Lee, Cárdenas-Hagan, Elsa, Francis, David J., Powell, Jennifer, Moore, Sarah, Haynes, Erin F.

Journal:

Journal of Research on Educational Effectiveness

Year:

2014

Language:

english

File:

PDF, 512 KB

english, 2014

15

Long-term genetic stability and a high-altitude East Asian origin for the peoples of the high valleys of the Himalayan arc

Jeong, Choongwon, Ozga, Andrew T., Witonsky, David B., Malmström, Helena, Edlund, Hanna, Hofman, Courtney A., Hagan, Richard W., Jakobsson, Mattias, Lewis, Cecil M., Aldenderfer, Mark S., Di Rienzo, A

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.48 MB

english, 2016

16

The Use of Microtechnology to Monitor Collision Performance in Professional Rugby Union

MacLeod, Simon J, Hagan, Chris, Egaña, Mikel, Davis, Jonny, Drake, David

Journal:

International Journal of Sports Physiology and Performance

Year:

2018

Language:

english

File:

PDF, 388 KB

english, 2018

17

Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers

Uddin, Golam M., Youngson, Neil A., Chowdhury, Sabiha S., Hagan, Christopher, Sinclair, David A., Morris, Margaret J.

Journal:

Year:

2020

File:

PDF, 2.20 MB

2020

18

Catalytic Asymmetric Fluorination Comes of Age

Vincent A. Brunet, David O'Hagan

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 316 KB

english, 2008

19

Enzymatic Fluorination in Streptomyces cattleya Takes Place with an Inversion of Configuration Consistent with an SN2 Reaction Mechanism

Cosimo D. Cadicamo, Jacques Courtieu, Hai Deng, Abdelkrim Meddour, David O'Hagan

Journal:

Year:

2004

Language:

english

File:

PDF, 160 KB

english, 2004

20

Synthesis and Vanilloid Receptor (TRPV1) Activity of the Enantiomers of α-Fluorinated Capsaicin

Margit Winkler, Thomas Moraux, Hesham A. Khairy, Roderick H. Scott, Alexandra M. Z. Slawin, David O'Hagan

Journal:

Year:

2009

Language:

english

File:

PDF, 385 KB

english, 2009

21

Mechanistic Insights into the Cytochrome P450-Mediated Oxidation and Rearrangement of Littorine in Tropane Alkaloid Biosynthesis

Pitak Nasomjai, Darwin W. Reed, David J. Tozer, Michael J. G. Peach, Alexandra M. Z. Slawin, Patrick S. Covello, David O'Hagan

Journal:

Year:

2009

Language:

english

File:

PDF, 424 KB

english, 2009

22

ChemInform Abstract: Extreme Enantiomeric Discrimination of Fluoroalkanes Using Deuterium NMR in Chiral Liquid Crystalline Media.

Mustafa Tavasli, Jacques Courtieu, Rebecca J. M. Goss, Abdelkrim Meddour, David O'Hagan

Journal:

Year:

2002

File:

PDF, 26 KB

2002

23

The first enzymatic method for C–18F bond formation: the synthesis of 5′-[18F]-fluoro-5′-deoxyadenosine for imaging with PET

Laurent Martarello, Christoph Schaffrath, Hai Deng, Antony D Gee, Andrew Lockhart, David O'Hagan

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2003

Language:

english

File:

PDF, 118 KB

english, 2003

24

In Vitro Reconstituted Biotransformation of 4-Fluorothreonine from Fluoride Ion: Application of the Fluorinase

Hai Deng, Stuart M. Cross, Ryan P. McGlinchey, John T.G. Hamilton, David O'Hagan

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 697 KB

english, 2008

25

Solid state and theoretical evaluation of β-fluoroethyl esters indicate a fluorine-ester gauche effect

Caroline R.S. Briggs, David O’Hagan, Henry S. Rzepa, Alexandra M.Z. Slawin

Journal:

Journal of Fluorine Chemistry

Year:

2004

Language:

english

File:

PDF, 673 KB

english, 2004

26

The role of organic fluorine in directing alkylation reactions via lithium chelation

Kenny Tenza, Julian S. Northen, David O’Hagan, Alexandra M.Z. Slawin

Journal:

Journal of Fluorine Chemistry

Year:

2004

Language:

english

File:

PDF, 291 KB

english, 2004

27

Synthesis of fluorinated analogues of the neurosteroid GABAA receptor antagonist, 17-PA

Gildas Deniau, Keith T. Sillar, David O’Hagan

Journal:

Journal of Fluorine Chemistry

Year:

2008

Language:

english

File:

PDF, 491 KB

english, 2008

28

Fluorine in health care: Organofluorine containing blockbuster drugs

David O’Hagan

Journal:

Journal of Fluorine Chemistry

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

29

A DFT study on the origin of the fluorine gauche effect in substituted fluoroethanes

David Y. Buissonneaud, Tanja van Mourik, David O'Hagan

Journal:

Year:

2010

Language:

english

File:

PDF, 872 KB

english, 2010

30

Lipase mediated preparation of the enantiomers of 3,3,3-trifluoro-2-methylpropanoic acid

Petr Beier, Alexandra M. Z. Slawin, David O’Hagan

Journal:

Tetrahedron: Asymmetry

Year:

2004

Language:

english

File:

PDF, 279 KB

english, 2004

31

Stereospecific benzylic dehydroxyfluorination reactions using Bio’s TMS-amine additive approach with challenging substrates

Stefano Bresciani, David O’Hagan

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 279 KB

english, 2010

32

The CF bond as a tool in the conformational control of amides

Caroline R.S. Briggs, David O’Hagan, Judith A.K. Howard, Dmitrii S. Yufit

Journal:

Journal of Fluorine Chemistry

Year:

2003

Language:

english

File:

PDF, 139 KB

english, 2003

33

Plant terpene biosynthesis. The biosynthesis of linalyl acetate in Mentha citrata

Daniel J Fowler, John TG Hamilton, Andrew J Humphrey, David O'Hagan

Journal:

Tetrahedron Letters

Year:

1999

Language:

english

File:

PDF, 210 KB

english, 1999

34

Fluorine in medicinal chemistry: A review of anti-cancer agents

Chukwuemeka Isanbor, David O’Hagan

Journal:

Journal of Fluorine Chemistry

Year:

2006

Language:

english

File:

PDF, 1.14 MB

english, 2006

35

Organofluorine Chemistry: Synthesis and Conformation of Vicinal Fluoromethylene Motifs

O’Hagan, David

Journal:

Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 586 KB

english, 2012

36

The Synthesis of η-1,2,3,4,5,6-Hexafluorocyclohexane (Benzene Hexafluoride) from Benzene

Alastair J. Durie, Prof. Alexandra M. Z. Slawin, Dr. Tomas Lebl, Prof. David O'Hagan

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 707 KB

english, 2012

37

A vapor phase deposition of self-assembled monolayers: Vinyl-terminated films of volatile silanes on silicon oxide substrates

Malgorzata Adamkiewicz, Tony O'Hara, David O'Hagan, Georg Hähner

Journal:

Thin Solid Films

Year:

2012

Language:

english

File:

PDF, 510 KB

english, 2012

38

Allosteric agonists of the calcium receptor (CaR): fluorine and SF5 analogues of cinacalcet

Chia, Poh Wai, Brennan, Sarah C., Slawin, Alexandra M. Z., Riccardi, Daniela, O'Hagan, David

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 463 KB

english, 2012

39

Fluorine in medicinal chemistry: β-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA

Campbell, Nancy H., Smith, Daniel L., Reszka, Anthony P., Neidle, Stephen, O'Hagan, David

Journal:

Organic & Biomolecular Chemistry

Year:

2011

Language:

english

File:

PDF, 719 KB

english, 2011

40

Fluorocyclohexanes: synthesis and structure of all-syn-1,2,4,5-tetrafluorocyclohexane

Durie, Alastair J., Slawin, Alexandra M. Z., Lebl, Tomas, Kirsch, Peer, O'Hagan, David

Journal:

Chemical Communications

Year:

2012

Language:

english

File:

PDF, 1.46 MB

english, 2012

41

Multi-vicinal fluoroalkanes: a new class of organofluorine compounds

Hunter, Luke, O'Hagan, David

Journal:

Organic & Biomolecular Chemistry

Year:

2008

Language:

english

File:

PDF, 487 KB

english, 2008

42

Insights into fluorometabolite biosynthesis in Streptomyces cattleya DSM46488 through genome sequence and knockout mutants

Chunhua Zhao, Peng Li, Zixin Deng, Hong-Yu Ou, Ryan P. McGlinchey, David O’Hagan

Journal:

Bioorganic Chemistry

Year:

2012

Language:

english

File:

PDF, 628 KB

english, 2012

43

Structure of Hydrous Ruthenium Oxides: Implications for Charge Storage

McKeown, David A., Hagans, Patrick L., Carette, Linda P. L., Russell, Andrea E., Swider, Karen E., Rolison, Debra R.

Journal:

Journal of Physical Chemistry B

Year:

1999

Language:

english

File:

PDF, 127 KB

english, 1999

44

Liquid crystals carrying stereodefined vicinal difluoro- and trifluoro- alkyl motifs

Nicoletti, Marcello, Bremer, Matthias, Kirsch, Peer, O'Hagan, David

Journal:

Chemical Communications

Year:

2007

Language:

english

File:

PDF, 260 KB

english, 2007

45

Development of a Robust and Repeatable UPLC−MS Method for the Long-Term Metabolomic Study of Human Serum

Zelena, Eva, Dunn, Warwick B., Broadhurst, David, Francis-McIntyre, Sue, Carroll, Kathleen M., Begley, Paul, O’Hagan, Steve, Knowles, Joshua D., Halsall, Antony, Wilson, Ian D., Kell, Douglas B.

Journal:

Analytical Chemistry

Year:

2009

Language:

english

File:

PDF, 1.88 MB

english, 2009

46

The influence of vicinal threo-difluorination on electro-optic and mesogenic properties of propyleneoxy-linked nematic liquid crystals

Al-Maharik, Nawaf, Kirsch, Peer, Slawin, Alexandra M.Z., O'Hagan, David

Journal:

Year:

2014

Language:

english

File:

PDF, 531 KB

english, 2014

47

Successful fluorine-containing herbicide agrochemicals

Fujiwara, Tomoya, O’Hagan, David

Journal:

Journal of Fluorine Chemistry

Year:

2014

Language:

english

File:

PDF, 3.71 MB

english, 2014

48

A Localized Tolerance in the Substrate Specificity of the Fluorinase Enzyme enables “Last-Step” 18 F Fluorination of a RGD Peptide under Ambient Aqueous Conditions

Thompson, Stephen, Zhang, Qingzhi, Onega, Mayca, McMahon, Stephen, Fleming, Ian, Ashworth, Sharon, Naismith, James H., Passchier, Jan, O'Hagan, David

Journal:

Angewandte Chemie International Edition

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

49

Analysis of CF···FC Interactions on Cyclohexane and Naphthalene Frameworks

Cormanich, Rodrigo A., Rittner, Roberto, O’Hagan, David, Bühl, Michael

Journal:

Journal of Physical Chemistry A

Year:

2014

Language:

english

File:

PDF, 552 KB

english, 2014

50

Stereoelectronic Interactions and the One-Bond C–F Coupling Constant in Sevoflurane

Freitas, Matheus P., Bühl, Michael, O’Hagan, David, Cormanich, Rodrigo A., Tormena, Cláudio F.

Journal:

Journal of Physical Chemistry A

Year:

2012

Language:

english

File:

PDF, 2.51 MB

english, 2012